Anti-EAPII (TTRAP) antibody produced in rabbit

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免疫原

peptide corresponding to the human EAPII (amino acids 11-28).

应用

Anti-EAPII (TTRAP) antibody produced in rabbit is suitable for western blot analysis at a working dilution of 1:1000-1:5000.

生化/生理作用

Ets proteins are a family of conserved sequence specific DNA-binding proteins. They function as transcription factors with roles in differentiation, lymphoid cell development, invasiveness, and angiogenesis. ETS1-associated protein II (EAPII) interacts with ETS1 and other Ets proteins (ETS2 and FLI1). EAPII is mainly localized to the nucleus of mammalian cells. EAPII negatively modulates the transcriptional activity of ETS1. It reduces synergistic transactivation by ETS1 and AP-1. Re-expression of EAPII prevents the migration of epithelial cancer cells. It does not affect cell viability.

外形

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

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