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Anti-EN-RAGE antibody produced in goat

品牌
Sigma-Aldrich
货号
E1032
规格纯度
affinity isolated antibody, lyophilized powder
价格
8124.33 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-EN-RAGE antibody produced in goat
Anti-CAGC
Anti-p6
Anti-S100A12
Anti-S100 calcium binding protein A12
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

EN-RAGE is a member of the S100/calgranulin superfamily.

免疫原

purified,E. coli-derived recombinant human extracellular RAGE-binding protein.

应用

Anti-EN-RAGE antibody produced in goat is suitable for western blot analysis at a working concentration of 0.1–0.2μg/mL, immunohistochemistry at 5-15μg/mL and flow cytometry at 3-10μg/mL/106cells.

生化/生理作用

The gene encodes a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It stimulates innate immune cells via binding to receptor for advanced glycation end products (AGER), which activates the MAP-kinase and NF-κ-B signaling pathways leading to production of proinflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1. It also stimulates mast cell degranulation and activation which generates chemokines, histamine and cytokines with leukocyte recruitment to the sites of inflammation.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

半岛bd体育手机客户端 性质

质量水平 100
生物来源 goat
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 lyophilized powder
species reactivity human
technique(s) flow cytometry: 3-10 μg/mL
immunohistochemistry: 5-15 μg/mL
western blot: 0.1-0.2 μg/mL
UniProt登记号 P80511
储存温度 ?20℃
Gene Information human ... S100A12(6283)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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