半岛bd体育手机客户端 说明

特异性

The epitope is highly conserved in human, swine, bovine and chicken ET-A.

免疫原

synthetic peptide corresponding to amino acids 413-426 of rat ET-A (with additional N-terminal cysteine).

应用

Anti-Endothelin Receptor A antibody produced in rabbit is suitable for immunohistochemistry at a dilution of 1:100 using rat brain sections or rat lung paraffin embedded sections and western blotting at a dilution of 1:200 using rat brain membranes and ECL.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

生化/生理作用

Endothelin receptor type A (ETA, ETAR) is a human G protein-coupled receptor that mediates vasoconstriction of blood vessels. It is involved in tumor cell invasion, survival and metastasis. ETAR mediates the promotion of ET-1 on colon cancer cell survival, invasion and MMP-2 expression by a PI3K-mediated mechanism. It plays a critical role in colon cancer metastasis.

外形

Lyophilized from a solution of phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD01092540
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	lyophilized powder
species reactivity	human, pig, bovine, chicken
technique(s)	immunohistochemistry: 1:100 using rat brain sections or rat lung paraffin embedded sections western blot: 1:200 using rat brain membranes and ECL
UniProt登记号	P25101
运输	dry ice
储存温度	?20℃
Gene Information	human ... EDNRA(1909) rat ... Ednra(24326)

安全信息

危险声明	H412
预防措施声明	P273
危险分类	Aquatic Chronic 3
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable