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Dipeptidyl Peptidase VIII human

品牌
Sigma-Aldrich
货号
D3196
规格纯度
recombinant, expressed inSf9 cells
价格
8308.42 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Dipeptidyl Peptidase VIII human
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Human dipeptidyl peptidase VIII has been used in a study to identify ERGIC-53 as an intracellular transport receptor of α1-antitrypsin. Human dipeptidyl peptidase VIII has also been used in a study to investigate the cargo selectivity of the ERGIC-53/MCFD2 transport receptor complex.

生化/生理作用

Dipeptidyl peptidase VIII (DPP8) is a 100 kDa monomeric protein expressed in the cytoplasm. It is a postproline dipeptidyl aminopeptidase that is homologous to DPPIV and fibroblast activation protein (FAP). It hydrolyzes Ala-Pro, Arg-Pro and Gly-Pro. DPP8 has a neutral pH optimum. It may be involved in T-cell activation and immune function as it is similar to DPPIV . It is upregulated during immune activation.

物理属性

Full length sequence with an N-terminal GST tag

单位定义

One unit will hydrolyze 1.0 picomole of Ala-Pro-AMC per minute at pH 7.4 at 25 deg ℃

外形

Supplied as a solution in 40 mM Tris-HCL, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM Glutathione, 3 mM DTT and 20% glycerol.

基本信息

NACRES NA.54

半岛bd体育手机客户端 性质

质量水平 200
重组 expressed inSf9 cells
形式 solution
specific activity ≥20 units/μg protein
分子量 100 kDa
浓度 ≥0.08 mg/mL
运输 dry ice
储存温度 ?70℃

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1

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