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DS1

品牌
Sigma-Aldrich
CAS
372497-52-4
货号
D0446
包装型号
规格纯度
≥98% (HPLC)
价格
2551.28 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
372497-52-4
DS1
4-Chloro-N-[6,8-dibromo-2-(2-thienyl)imidazo[1,2-a]pyridine-3-yl]benzamide
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

包装

5, 25 mg in glass bottle

生化/生理作用

δ-GABAAreceptors are emerging as an important pharmacological target. DS1 potently (low nM) enhances GABA-evoked currents mediated by α4β3δ receptors. It had little effect on GABA responses mediated by α4β3γ2 receptors. At similar concentrations DS1 directly activates this receptor and is the most potent known agonist of α4β3δ receptors. This compound has an opportunity to be become an agonist golden stardard for δ-GABAAreceptors.
DS1 potently (low nM) enhances GABA-evoked currents mediated by GABAAα4β3δ receptor subtype. At similar concentrations, it acts as a direct agonist at this receptor and is the most potent agonist known. It has little effect on GABA responses mediated by α4β3γ2 receptors.

基本信息

经验(实验)分子式 C18H10Br2ClN3OS
分子量 511.62
MDL编号 MFCD01943217
PubChem化学物质编号 329798608

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
储存条件 desiccated
颜色 off-white to tan
溶解性 DMSO: >10 mg/mL
储存温度 2-8℃
SMILES string Clc1ccc(cc1)C(=O)Nc2c(nc3c(Br)cc(Br)cn23)-c4cccs4
InChI 1S/C18H10Br2ClN3OS/c19-11-8-13(20)16-22-15(14-2-1-7-26-14)17(24(16)9-11)23-18(25)10-3-5-12(21)6-4-10/h1-9H,(H,23,25)
InChI key MEWSBNIVOLYKGU-UHFFFAOYSA-N

Sigma-Aldrich

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