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Cystatin C, Human Urine-Calbiochem

品牌
Sigma-Aldrich
货号
240896
规格纯度
A low molecular weight non-glycosylated basic protein of the cystatin superfamily of cysteine protease inhibitors that it is freely filtered by the glomerular membrane.
价格
1763.65 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Cystatin C, Human Urine-Calbiochem
Post γ-globulin
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

A low molecular weight non-glycosylated basic protein of the cystatin superfamily of cysteine protease inhibitors that it is freely filtered by the glomerular membrane. Serum levels of cystatin C can be used as a specific and sensitive marker of glomerular filtration rate. Protects organisms against undesirable proteolysis by endogenous or exogenous enzymes. Thought to be linked to many disease processes including Alzheimer’s disease, hereditary cerebral hemorrhage, and lung cancer.
A low molecular weight non-glycosylated basic protein of the cystatin superfamily of cysteine protease inhibitors that is freely filtered by the glomerular membrane. Serum levels of cystatin C can be used as a specific and sensitive marker of glomerular filtration rate. Protects organisms against undesirable proteolysis by endogenous or exogenous enzymes. Rapidly and tightly inhibits papain (Ki= 0.26 nM) and cathepsin B (Ki= 4.4 nM). Thought to be linked to many disease processes including Alzheimer′s Disease, hereditary cerebral hemorrhage and lung cancer.

包装

50 μg in Plastic ampoule

生化/生理作用

Primary Target
Cysteine protease
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Standard Handling (A)

外形

Lyophilized from 20 mM NH?HCO?.

制备说明

Prepared from the urine of patients with chronic renal tubular proteinuria that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

重悬

Following reconstitution, store in the refrigerator at 4°C. Stock solutions are stable for up to 2 month when stored at -20°C.

其他说明

Hall, A., et al. 1998.Biochemistry37,4071.
Peloille, S., et al. 1997.Eur. J. Biochem.244,140.
Cimerman, N., et al. 1996.Biol. Chem. Hoppe Seyler377,19.
Tenstad, O., et al. 1996.Scand. J. Clin. Lab. Invest.56,409.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥95% (SDS-PAGE)
形式 solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
溶解性 0.1 M sodium acetate, pH 4.5: soluble
运输 ambient
储存温度 2-8℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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