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APRIL human

品牌
Sigma-Aldrich
货号
SRP3008
规格纯度
recombinant, expressed in Hi-5 Insect cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture
价格
4582.93 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
APRIL human
A Proliferating-inducing Ligand
TNFSF13
TRDL-1?
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. APRIL, along with another TNF family member, BAFF, compete for two receptors, TACI and BCMA. ARPIL has the ability to stimulate proliferation of various tumor cell lines including Jurkat T cells and MCF-7 carcinoma cells. Like BAFF, APRIL also stimulates the proliferation of B and T cells. The human APRIL gene codes for at least four alternatively spliced transcriptional variants, which give rise to different isoforms of the APRIL precursor protein. All isoforms can be cleaved by the protease, furin, to release a soluble C-terminal fragment, which comprises the TNF like receptor binding of the APRIL precursor. Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues. 11

生化/生理作用

APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues.

序列

AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT EVMWQPALRR GRGLQAQGYG VRIQDAGVYL LYSQVLFQDV TFTMGQVVSR EGQGRQETLF RCIRSMPSHP DRAYNSCYSA GVFHLHQGDI LSVIIPRARA KLNLSPHGTF LGFVKL

外形

Lyophilized from 20 mM Sodium Acetate, pH 7.5 + 500 mM NaCl.

重悬

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed in Hi-5 Insect cells
测定 ≥95% (HPLC)
≥95% (SDS-PAGE)
形式 lyophilized
分子量 16.3 kDa
包装 pkg of 10 μg
technique(s) cell culture | mammalian: suitable
杂质 <0.1 EU/μg endotoxin, tested
颜色 white to off-white
UniProt登记号 O75888
运输 wet ice
储存温度 ?20℃
Gene Information human ... TNFSF13(8741)

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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