C6-NBD Glucosyl Ceramide

半岛bd体育手机客户端 说明

一般描述

C6-NBD Glucosyl Ceramide is a fluorescent derivative of biologically active compound, glucosyl ceramide. Glucosyl ceramide belongs to the class of sphingolipids that are synthesized in the cis/medial-Golgi apparatus by the glycosylation of ceramide.

应用

C6-NBD Glucosyl Ceramide may be used as a substrate for glucocerebrosidase (GCase) activity assay in Drosophila melanogaster and mice.

生化/生理作用

Glucosylceramide is the precursor of different glycosphingolipids including gangliosides and sulfatides. Glucosyl ceramide is also known to be responsible for axon growth of neural cells. The accumulation of glucosyl ceramide is associated with an inherited lysosomal storage disorder, Gaucher′s disease.

包装

5 mL Clear Glass Sealed Ampule (810222C-250ug)

基本信息

经验(实验)分子式	C36H59N5O11
分子量	737.88
NACRES	NA.25

半岛bd体育手机客户端 性质

测定	>99% (TLC)
包装	pkg of 1 × 1 mL (810222C-250ug)
manufacturer/tradename	Avanti Polar Lipids 810222C
浓度	0.25 mg/mL (810222C-250ug)
运输	dry ice
储存温度	?20℃

安全信息

象形图
警示用语：	Danger
危险声明	H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372
预防措施声明	P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
危险分类	Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官	Central nervous system
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	does not flash
闪点(C)	does not flash