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CDK5/p25, active, GST tagged human

品牌
Sigma-Aldrich
货号
C0745
规格纯度
PRECISIO?Kinase, recombinant, expressed in baculovirus infectedSf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
6484.55 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
CDK5/p25, active, GST tagged human
NCK5A
CDK5P35
CDK5R
p35nck5a
PSSALRE
p35
p23
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

质量水平 200
重组 expressed in baculovirus infectedSf9 cells
半岛bd体育手机客户端 线 PRECISIO?Kinase
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
specific activity 583-789 nmol/min·mg
分子量 CDK5 subunit ~59 kDa
p25 subunit ~49 kDa
UniProt登记号 Q00535
Q15078
运输 dry ice
储存温度 ?70℃
Gene Information human ... CDK5(1020), CDK5R1(8851)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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