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CDK2/CyclinE1, active, GST tagged human

CDK2/CyclinE1,活性,GST 标记 人

品牌
Sigma-Aldrich
货号
C0999
规格纯度
PRECISIO?Kinase, recombinant, expressed in baculovirus infectedSf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
6484.55 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
CDK2/CyclinE1, active, GST tagged human
CCNE1
p33
CDK2/CyclinE1,活性,GST 标记 人
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

CDK2 is a member of the Cyclin-Dependent Kinase family that is ubiquitously expressed. CDK2 is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. CDK2 associates with and is regulated by the regulatory subunits of the complex including Cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). CDK2 phosphorylates multiple cellular substrates including SMAD3 and FOXO1. Phosphorylation of FOXO1 leads to its inhibition.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

质量水平 200
重组 expressed in baculovirus infectedSf9 cells
半岛bd体育手机客户端 线 PRECISIO?Kinase
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
specific activity 343-464 nmol/min·mg
分子量 CDK2 subunit ~58 kDa
cyclin E1 ~73 kDa
UniProt登记号 P24864
P24941
运输 dry ice
储存温度 ?70℃
Gene Information human ... CCNE1(898), CDK2(1017)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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