Anti-Calcium Channel (γ₄Subunit) (Voltage Gated Ca²⁺Channel) antibody produced in rabbit

半岛bd体育手机客户端 说明

特异性

Specifically recognizes a splice variant of γ₄(36.5 kDa) from human, mouse and rat.

免疫原

synthetic peptide derived from the rat γ₄calcium channel subunit conjugated to KLH.

应用

Anti-Calcium Channel (γ4 Subunit) (Voltage Gated Ca²⁺Channel) antibody produced in rabbit is suitable for western blotting at a concentration of 5-10μg/mL using rat brain tissue lysate.

生化/生理作用

Voltage-dependent calcium channel γ-4 subunit is a protein encoded by the CACNG4 gene in humans and the three novel Ca²⁺channel γ subunit genes (CACNG3, CACNG4, and CACNG5) are mapped on chromosome 16 and 17. It is a transmembrane protein that may act as both neuronal voltage-dependent calcium channel (VDCC) γ subunits and transmembrane α-amino-3-hydroxy-5-methyl-4-isoxazoleproponinc (AMPA) receptor regulatory proteins (TARPs). CACNG4 is found to be expressed in the CNS and display differential distributions among brain regions and several cell types in found in the cerebellum and hippocampus. It plays a key role in VDCC function. CACNG4 function as regulators of AMPA receptor localization and function in the brain and are collectively known as TARPs.

外形

Phosphate buffered saline containing 0.08% sodium azide.

基本信息

MDL编号	MFCD06201927
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	200
偶联物	unconjugated
抗体形式	fractionated antiserum
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	mouse, rat, human
浓度	~1 mg/mL
technique(s)	western blot: 5-10 μg/mL using rat brain tissue lysate
UniProt登记号	Q9UBN1
运输	wet ice
储存温度	?20℃
Gene Information	human ... CACNG4(27092) mouse ... Cacng4(54377) rat ... Cacng4(140725)