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Monoclonal Anti-CD3 antibody produced in mouse

品牌
Sigma-Aldrich
货号
C7048
规格纯度
clone UCHT-1, purified immunoglobulin, buffered aqueous solution
价格
4731.57 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-CD3 antibody produced in mouse
Monoclonal Anti-CD3
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

特异性

Recognizes the CD3 complex. The epitope recognized by clone no. UCHT-1 is expressed on the ε-chain of the CD3 antigen/T cell receptor complex. 3rd Workshop: code no. 126, 208 and 471
4th Workshop: paper no. T3.2

免疫原

human thymocytes followed by Sezary T cells.

应用

Monoclonal Anti-CD3 antibody produced in mouse is suitable for flow cytometry at a dilution of 5μL using 1 × 106cells.

生化/生理作用

The CD3e cytoplasmic domain of the T cell receptor binds to the inner leaflet of the plasma membrane (PM) and is accessible during early stages of T cell activation. It is specific for T lymphocytes, found in Purkinje cells of the cerebellum and gastric parietal cells of humans and other species. The antibodies commonly used to recognize CD3 are directed against the ε-subunit of the T cell receptor. Cytoplasmic cyCD3 expression can only be achieved during the early phase of NK-cell differentiation.

目标描述

The CD3 complex (16/20/29/22/25-28 kDa) consists of 5 polypeptide chains associated with each other and with the T cell receptor.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 200
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 UCHT-1, monoclonal
形式 buffered aqueous solution
species reactivity human
technique(s) flow cytometry: 5 μL using 1 × 106cells
同位素/亚型 IgG1
UniProt登记号 P07766
运输 wet ice
储存温度 2-8℃
Gene Information human ... CD3E(916)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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