您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-CUGBP2 小鼠抗

Anti-CUGBP2 antibody, Mouse monoclonal

Monoclonal Anti-CUGBP2 小鼠抗

品牌
Sigma-Aldrich
货号
C9367
规格纯度
clone HL1889 (1H2-1F12), purified from hybridoma cell culture
价格
4731.57 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-CUGBP2 antibody, Mouse monoclonal
Anti-ETR3, RNA-binding protein
Anti-CUG Triplet Repeat, RNA-binding protein 2
Monoclonal Anti-CUGBP2 小鼠抗
Anti-ETR3
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

divergent domain of human CUGBP2 corresponding to amino acids 209-415 (accession no. NP006552).

应用

Suitable for immunocytochemistry, immunoprecipitation and western blotting at a working concentration of 30-40 μg/mL using total cell extract of mouse heart.

生化/生理作用

CUGBP2 is an RNA-binding protein that specifically binds to CUG repeat sequences and is responsible for the regulation of both nuclear and cytoplasmic RNA processing events such as alternative splicing, RNA editing, mRNA stability, and translation. It is mainly expressed in muscle and brain. It regulates a specific alternative slicing of exons 5 and 21 of the N-methyl-D-aspartate receptor 1 (NMDA R1) RNA in rat. It binds to U/G-rich motifs within muscle specific enhancer elements (MSEs) and activates inclusion of an alternative exon in cardiac troponin T (cTNT) pre-mRNAs. It interacts with A/U rich sequences in the 3′ UTR and inhibits translation of cycloxygenase-2 (COX-2) mRNAs.

目标描述

CUGBP2 is an RNA-binding protein that specificallybinds to CUG repeat sequences.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD09265421
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 200
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 HL1889 (1H2-1F12), monoclonal
形式 buffered aqueous solution
分子量 antigen ~52 kDa
species reactivity human, mouse, chicken
浓度 ~1.5 mg/mL
technique(s) immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: 30-40 μg/mL using total cell extract of mouse heart
同位素/亚型 IgG1
运输 dry ice
储存温度 ?20℃
Gene Information chicken ... CUGBP2(374111)
human ... CUGBP2(10659)
mouse ... Cugbp2(14007)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map