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Cromakalim

品牌
Sigma-Aldrich
CAS
94470-67-4
货号
C1055
包装型号
规格纯度
价格
2490.59 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
94470-67-4
Cromakalim
(±)- trans-6-Cyano-3,4-dihydro-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-2H-1-benzopyran-3-ol
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Cromakalim has been used:

  • as a potassium channel agonist to study its response to an acute increase in downstream pressure in rat lymphatic vessels.
  • as a potassium channel opener to study its effects on the release of transmitters from adrenergic nerves in rat vas deferens.
  • as a potassium channel activator to study its effects on the release of transmitters from purinergic and cholinergic nerves in the rat detrusor muscle.

包装

10, 50 mg in glass bottle

生化/生理作用

Cromakalim is an activator of the potassium channel. It is involved in the relaxation of the vascular smooth muscles. Cromakalim exhibits anti-hypertensive activity.

特点和优势

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式 C16H18N2O3
分子量 286.33
MDL编号 MFCD00133201
PubChem化学物质编号 24891962
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 200
储存温度 2-8℃
SMILES string CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)N3CCCC3=O)C#N
InChI 1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3/t14-,15+/m1/s1
InChI key TVZCRIROJQEVOT-CABCVRRESA-N
Gene Information rat ... Kcna1(24520), Kcnj1(24521), Kcnj5(29713), Kcnj8(25472)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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