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Caspase 10 human

品牌
Sigma-Aldrich
货号
C6607
规格纯度
>90% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, 8,000 units/mg protein (Bradford)
价格
4174.14 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
半岛bd体育手机客户端 名称:
Caspase 10 human
Flice2
Mch4
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

包装

25, 100 units in glass bottle

生化/生理作用

Caspase 10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors. Caspase 10 cleaves and activates caspases 3, 4, 6, 7, 8 and 9 which causes the proteolytic cleavage of many key proteins such as PARP. Based on gene expression studies, caspase 10 may be crucial in embryonic development. In view of its structural homology to caspase 8, the initiator caspase in death receptor-mediated apoptosis, caspase 10 may function in a similar and redundant manner.

单位定义

One unit will hydrolyze 1 nmol of the caspase substrate IETD-pNA to IETD and p-nitroaniline per hour at pH 7.2 at 37 ℃.

外形

Lyophilized powder containing 0.052% ammonium sulfate, 0.158% Tris−HCl, and 0.76% sodium chloride.

基本信息

MDL编号MFCD03456342
NACRESNA.32

半岛bd体育手机客户端 性质

质量水平200
重组expressed in E. coli
测定>90% (SDS-PAGE)
形式lyophilized powder
specific activity8,000 units/mg protein (Bradford)
分子量 ~30 kDa
溶解性PBS: soluble
UniProt登记号Q92851
运输dry ice
储存温度−70℃
Gene Informationhuman ... CASP10(843)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

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