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Cyclothiazide

品牌
Sigma-Aldrich
CAS
2259-96-3
货号
C9847
包装型号
规格纯度
价格
1249.07 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
2259-96-3
Cyclothiazide
6-Chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2-4-benzothiadiazine-7-sulfonamide 1,1-dioxide
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Cyclothiazide is a benzothiadiazine, which has a similar structure to diazoxide.

应用

Cyclothiazide has been used as a α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) desensitization blocker to study the effects of γ2 on receptor desensitization.

包装

10 mg in poly bottle
25 mg in glass bottle

生化/生理作用

Blocks the rapid desensitization of the AMPA glutamate receptors and markedly prolongs the decay time of the evoked excitatory post-synaptic current.

特点和优势

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式 C14H16ClN3O4S2
分子量 389.88
EC 号 218-859-7
MDL编号 MFCD00210192
PubChem化学物质编号 24278350
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 200
创始人 Eli Lilly
储存温度 2-8℃
SMILES string [H][C@@]12CC(C3Nc4cc(Cl)c(cc4S(=O)(=O)N3)S(N)(=O)=O)[C@@]([H])(C1)C=C2
InChI 1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20)/t7-,8+,9?,14?/m0/s1
InChI key BOCUKUHCLICSIY-QJWLJZLASA-N
Gene Information human ... CA1(759), CA4(762), GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893)
rat ... Gria1(50592)

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 dust mask type N95 (US), Eyeshields, Gloves

Sigma-Aldrich

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