半岛bd体育手机客户端 说明
应用
N6-Cyclopentyladenosine has been used to study its effect on the cavernosal smooth muscle cells from lean and db/db (obesity and type II diabetes caused by a leptin receptor mutation) mice.
N6-Cyclopentyladenosine has also been used to study its effect on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line.
包装
25 mg in poly bottle
100 mg in glass bottle
生化/生理作用
N6-Cyclopentyladenosine (CPA) is an adenosine derivative and a potent A1 adenosine receptor agonist. It acts as an anticonvulsant and might exhibit protective actions against aminophylline (AMPH)-induced seizures.
N6-Cyclopentyladenosine also exhibits analgesic effect against acute, arthritis-induced and neuropathic pain.
特点和优势
This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
外形
hygroscopic solid
基本信息
| 经验(实验)分子式 | C15H21N5O4 |
| 分子量 | 335.36 |
| MDL编号 | MFCD00036845 |
| PubChem化学物质编号 | 24277686 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 200 |
| 形式 | solid |
| 颜色 | white to off-white |
| 溶解性 | H2O: 1.7 mg/mL 0.1 M HCl: 12 mg/mL DMSO: 23 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NC4CCCC4)ncnc23 |
| InChI | 1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15-/m1/s1 |
| InChI key | SQMWSBKSHWARHU-SDBHATRESA-N |
| Gene Information | human ... ADORA1(134), ADORA2A(135), ADORA3(140) mouse ... Adora1(11539) rat ... Adora1(29290), Adora2a(25369), Adora3(25370) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
