18:1 EPC (Cl Salt)

半岛bd体育手机客户端 说明

一般描述

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) is a cationic alkylated phospholipid.

应用

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt) (18:1 EPC (Cl Salt)) is suitable:

• for composing lipid shell to prepare lipopolyplex/mRNA vaccine
• in solvent-assisted preparation of supported lipid bilayers
• along with 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) in mixed liposomes as colloidal vectors for physicochemical study of the DNA compaction
• to formulate the lipid nanoparticle (LNP1) to enhance intracellular delivery mediated by shock waves

生化/生理作用

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) serves as a transfection reagent. 18:1 EPC is applicable in liposomes and lipoplexes. It is a potential vector in gene therapy.

包装

5 mL Clear Glass Sealed Ampule (890704C-100mg)
5 mL Clear Glass Sealed Ampule (890704C-25mg)
5 mL Clear Glass Sealed Ampule (890704C-200mg)

基本信息

经验(实验)分子式	C46H89NO8PCl
分子量	850.63
NACRES	NA.25

半岛bd体育手机客户端 性质

包装	pkg of 1 × 2.5 mL (890704C-25mg) pkg of 1 × 4 mL (890704C-100mg) pkg of 2 × 4 mL (890704C-200mg)
manufacturer/tradename	Avanti Polar Lipids 890704C
浓度	10 mg/mL (890704C-25mg) 25 mg/mL (890704C-100mg) 25 mg/mL (890704C-200mg)
运输	dry ice
储存温度	?20℃
SMILES string	O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)OCC.[Cl-]

安全信息

象形图
警示用语：	Danger
危险声明	H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412
预防措施声明	P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
危险分类	Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官	Central nervous system
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	does not flash
闪点(C)	does not flash