半岛bd体育手机客户端 说明
一般描述
Ataxia telangiectasia group D-complementing (ATDC) protein, also known as tripartite motif containing protein 29 (TRIM29), belongs to the TRIM protein family. Studies have shown that ATDC may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. The ATDC gene is located at 11q23 where loss of heterozygosity has been observed in many kinds of cancers; underexpression of ATDC has been reported in breast and prostate cancer. ATDC may also complement the radiosensitivity defect of ataxia telangiectasia phenotype.
免疫原
KLH-conjugated linear peptide corresponding to a region within amino acides 565 to 595 of human ATDC .
应用
Research Sub Category
Transcription Factors
Anti-ATDC Antibody is a Rabbit Polyclonal Antibody for detection of ATDC also known as Ataxia telangiectasia group D-associated protein & has been validated in WB & IP.
Research Category
Epigenetics & Nuclear Function
Immunoprecipitation Analysis: A representative lot was used by an independent laboratory in IP. (Yuan, Z., et al. (2010). J Biol Chem. 285(50):39329-39338.)
质量
Evaluated by Western Blot in RAW 264.7 cell lysate.
Western Blot Analysis: 1 ?g/mL of this antibody detected ATDC on 10 ?g of RAW 264.7 cell lysate.
目标描述
~66 kDa observed
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
RAW 264.7 cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | rat, human, mouse |
technique(s) | immunoprecipitation (IP): suitable western blot: suitable |
NCBI登记号 | NP_036233 |
UniProt登记号 | Q14134 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich