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IL-36 BETA human

品牌
Sigma-Aldrich
货号
SRP3288
规格纯度
recombinant, expressed inE. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
价格
4234.11 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
IL-36 BETA human
IL-1F8
IL-1H2
IL-1 eta
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

IL-36β is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36β signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36β also functions as an agonist of NF-kappaB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3.

生化/生理作用

The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). Recombinant human IL-36β is a 17.3 kDa protein containing 154 amino acid residues.

外形

Lyophilized from 10 mM Sodium Phosphate, pH 7.0.

重悬

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed inE. coli
测定 ≥98% (HPLC)
≥98% (SDS-PAGE)
形式 lyophilized
分子量 17.3 kDa
包装 pkg of 10 μg
杂质 <0.1 EU/μg endotoxin, tested
颜色 white to off-white
UniProt登记号 Q9NZH8
运输 wet ice
储存温度 ?20℃
Gene Information human ... IL36G(56300)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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