Insulin-Like Growth Factor Binding Protein-2 human

半岛bd体育手机客户端 说明

一般描述

The gene IGFBP-2 (insulin-like growth factor binding protein-2) is mapped to human chromosome 2q35.

生化/生理作用

IGFBP-2 (insulin-like growth factor binding protein-2) regulates the function of IGF ligands. IGFBP2 is associated with skeletal muscle cell proliferation and differentiation. It also plays an important role in the differentiation of corneal fibroblast.
During development, insulin-like growth factor binding protein-2 is expressed in a number of tissues with the highest expression level found in the central nervous system. IGFBP-2 exhibits a 2-10 fold higher affinity for IGF II than for IGF I. Mouse and human IGFBP-2 share approximately 82% homology.

外形

Lyophilized from a 0.2 μm filtered solution of 30% (v/v) acetonitrile with 0.1% (v/v) TFA

分析说明

The biological activity is measured by its ability to inhibit recombinant human lGF-II on MCF-7 cells.

基本信息

MDL编号	MFCD02099094
NACRES	NA.32

半岛bd体育手机客户端 性质

质量水平	100
生物来源	human
重组	expressed in NSO cells
测定	≥95% (SDS-PAGE)
形式	lyophilized powder
效能	0.04 μg/mL
分子量	~36 kDa by SDS-PAGE calculated mol wt ~31 kDa
包装	pkg of 25 μg
储存条件	avoid repeated freeze/thaw cycles
technique(s)	cell culture | mammalian: suitable
杂质	endotoxin, tested
UniProt登记号	P18065
储存温度	?20℃
Gene Information	human ... IGFBP2(3485)

安全信息

象形图
警示用语：	Warning
危险声明	H319 - H332
预防措施声明	P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
危险分类	Acute Tox. 4 Inhalation - Eye Irrit. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves