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位置: 首页> 品牌> Sigma-Aldrich> Almotriptan Malate

Almotriptan Malate

品牌
Sigma-Aldrich
CAS
181183-52-8
货号
SML1210
规格纯度
≥98% (HPLC)
价格
1399.43 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
181183-52-8
Almotriptan Malate
PNU 180638
3-[2-(Dimethylamino)ethyl]-5-(pyrrolidin-1-ylsulfonylmethyl )-1H-indole malate
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Almotriptan is a serotonin 5HT-1B/1D-receptor agonist; antimigraine.
Almotriptan at an oral dose of 12.5 mg, is recommended to be safe for treating migraine.

生化/生理作用

Almotriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Almotriptan has low nanomolar affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower. Affinity for 5-HT(7) and 5-HT(1A) receptors was approximately 40 and 60 times lower than that for 5-HT(1B/1D) receptors, respectively.

基本信息

经验(实验)分子式 C17H25N3O2S · C4H6O5
分子量 469.55
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
储存条件 desiccated
颜色 white to beige
溶解性 H2O: 10 mg/mL, clear
储存温度 ?20℃
InChI 1S/C17H25N3O2S.C4H6O5/c1-19(2)10-7-15-12-18-17-6-5-14(11-16(15)17)13-23(21,22)20-8-3-4-9-20;5-2(4(8)9)1-3(6)7/h5-6,11-12,18H,3-4,7-10,13H2,1-2H3;2,5H,1H2,(H,6,7)(H,8,9)
InChI key QHATUKWEVNMHRY-UHFFFAOYSA-N

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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