N-(4-甲基-2-氨基磺酰基-Δ<SUP>2</SUP>-1,3,4-噻二唑-5-亚基)乙酰胺

醋甲唑胺

品牌

Sigma-Aldrich

CAS

554-57-4

货号

SML0720

包装型号

50 MG, ≥98% (HPLC)

规格纯度

≥98% (HPLC)

价格

1589.59 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

554-57-4
Methazolamide
5-Acetylimino-4-methyl-·2-1,3,4-thiadiazoline-2-sulfonamide
N-[5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
L 584601
N-(4-Methyl-2-sulfamoyl-Δ ²-1,3,4-thiadiazolin-5-ylidene) acetamide
醋甲唑胺
N-(4-甲基-2-氨基磺酰基-Δ ²-1,3,4-噻二唑-5-亚基)乙酰胺

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

包装

50 mg in glass bottle

生化/生理作用

Methazolamide has a plasma half-life of 14 hours in humans. Methazolamide has relatively good lipid solubility and low plasma protein binding ability. Thus, it diffuses into tissues and fluids much more readily than acetazolamide, another carbonic anhydrase inhibitor. Methazolamide has less side effects than acetazolamide.
Methazolamide is a cell-permeable and potent carbonic anhydrase (CA) inhibitor that is used in the treatment of glaucoma. Methazolamide is an insulin sensitizer that reduces hepatic glucose generation in animal models.

其他说明

Light sensitive

基本信息

经验(实验)分子式	C₅H₈N₄O₃S₂
分子量	236.27
EC 号	209-066-7
MDL编号	MFCD00083416
PubChem化学物质编号	329825590
NACRES	NA.77

半岛bd体育手机客户端性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	protect from light
颜色	white to beige
mp	208 ℃ (dec.) (lit.)
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃
SMILES string	CN1N=C(S\C1=N\C(C)=O)S(N)(=O)=O
InChI	1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4+
InChI key	FLOSMHQXBMRNHR-QPJJXVBHSA-N
Gene Information	human ... CA1(759), CA2(760), CA4(762), CA7(766)

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332 - H351
预防措施声明	P201 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable