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Trandolapril

群多普利

品牌
Sigma-Aldrich
CAS
87679-37-6
货号
T4827
规格纯度
≥98% (HPLC), white, powder
价格
2151.31 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
87679-37-6
Trandolapril
(2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid
Mavik
群多普利
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Trandolapril has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on responsiveness of human retinal endothelial cells (HRECs) to vascular endothelial growth factor (VEGF).

包装

10, 50 mg in glass bottle

生化/生理作用

Trandolapril is an ACE inhibitor. Trandolapril differs from other ACE inhibitors in that it has a longer biological half-life and a high degree of lipophilicity.
Studies have reported that trandolapril inhibits atherosclerosis1and decreases the occurrence of atrial fibrillation2.

特点和优势

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

制备说明

Trandolapril is soluble in DMSO at a concentration that is greater than or equal to 20 mg/ml.

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. T4827.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

基本信息

经验(实验)分子式 C24H34N2O5
分子量 430.54
MDL编号 MFCD00865776
PubChem化学物质编号 329826801
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
颜色 white
溶解性 DMSO: ≥20 mg/mL
创始人 Abbott
SMILES string CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2C3CCCCC3C[C@H]2C(O)=O
InChI 1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1
InChI key VXFJYXUZANRPDJ-WTNASJBWSA-N
Gene Information human ... ACE(1636)

安全信息

象形图 GHS08
警示用语: Danger
危险声明 H360D
预防措施声明 P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类 Repr. 1B
储存分类代码 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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