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Desloratadine

地氯雷他定

品牌
Sigma-Aldrich
CAS
100643-71-8
货号
D1069
规格纯度
powder, ≥98% (HPLC)
价格
2467.13 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
100643-71-8
Desloratadine
8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine
Clarinex
NSC 675447
地氯雷他定
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Desloratadine has been used to test its effect on embryoid body development in in vitro gastrulation model of P19C5 stem cells. It has also been used as an antihistamine mimic in rats and to treat lung cancer (A549) and glioblastoma (U87) cells in various cellular studies.

包装

10, 50 mg in glass bottle

生化/生理作用

Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. D1069.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

法律信息

Clarinex is a registered trademark of Schering Corp.

基本信息

经验(实验)分子式 C19H19ClN2
分子量 310.82
MDL编号 MFCD00871949
PubChem化学物质编号 329798668
NACRES NA.32

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
溶解性 DMSO: >10 mg/mL
储存温度 2-8℃
SMILES string Clc1ccc2c(CCc3cccnc3\C2=C4\CCNCC4)c1
InChI 1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
InChI key JAUOIFJMECXRGI-UHFFFAOYSA-N
Gene Information human ... HRH1(3269)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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