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位置: 首页> 品牌> Sigma-Aldrich> Anti-CD11b, (human/mouse), redFluor?710, clone M1/70 Antibody

Anti-CD11b, (human/mouse), redFluor?710, clone M1/70 Antibody

品牌
Sigma-Aldrich
货号
MABF80B
规格纯度
clone M1/70, from rat, redFluor?710
价格
1415.25 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-CD11b, (human/mouse), redFluor ?710, clone M1/70 Antibody
Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, CD11b, CD11b
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The M1/70 antibody is widely used as a marker for CD11b expression on mouse macrophages, granulocytes, neutrophils, and NK cells. The antibody is also reported to be cross-reactive for Rhesus macaque CD11b.

免疫原

Immunogen information for this antibody is proprietary information.

应用

Research Sub Category
Immunoglobulins & Immunology
This rat monoclonal Anti-CD11b Antibody, (human/mouse), redFluor?710, clone M1/70, Cat. No. MABF804 is validated for use in Flow Cytometry, for the detection of CD11b.
Research Category
Inflammation & Immunology

质量

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.25 μg from a representative lot detected CD11b in one million C57Bl/6 bone marrow cells.

外形

Purified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Purified by size-exclusion chromatography

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

其他说明

Concentration: Please refer to lot specific datasheet.

法律信息

redFluor is a registered trademark of Tonbo Biotechnologies

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 rat
偶联物 redFluor?710
抗体形式 purified antibody
antibody product type primary antibodies
克隆 M1/70, monoclonal
species reactivity human, mouse
包装 antibody small pack of 25 μg
technique(s) flow cytometry: suitable
同位素/亚型 IgG2bκ
UniProt登记号 P05555

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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