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位置: 首页> 品牌> Sigma-Aldrich> Anti-CD19 Antibody, APC Conjugated, (human), clone SJ25C1

Anti-CD19 Antibody, APC Conjugated, (human), clone SJ25C1

品牌
Sigma-Aldrich
货号
MABF164B
规格纯度
clone SJ25C1, from mouse, Allophycocyanin conjugate
价格
2668.07 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-CD19 Antibody, APC Conjugated, (human), clone SJ25C1
B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, CD antigen CD19
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The SJ25C1 antibody reacts with human CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21 (CR2), CD81 (TAPA-1) and CD225 (Leu13), in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. Upon activation and tyrosine phosphorylation, the CD19 molecule can provide an anchor for cytoplasmic signaling proteins such as GRB2, SOS or PLCG2. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.

The SJ25C1 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.

免疫原

Immunogen information for this antibody is proprietary information.

应用

This mouse monoclonal, Anti-CD19 (human), APC, clone SJ25C1, Cat. No. MABF1644 is validated for use in Flow Cytometry, for the detection of CD19.
Research Category
Inflammation & Immunology

质量

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Evaluated by Flow Cytometry in human peripheral blood lymphocytes.
Flow Cytometry Analysis (FC): 0.5 μg of this antibody detected CD19 in one million human peripheral blood lymphocytes.

外形

Purified mouse monoclonal in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Purified by size-exclusion chromatography

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 Allophycocyanin conjugate
抗体形式 purified antibody
antibody product type primary antibodies
克隆 SJ25C1, monoclonal
species reactivity human
technique(s) flow cytometry: suitable
同位素/亚型 IgG1κ
UniProt登记号 P15391
Gene Information human ... CD19(930)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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