(-)-Bilobalide fromGinkgo bilobaleaves

半岛bd体育手机客户端 说明

一般描述

Bilobalide is a biologically active terpenic trilactone (terpenoid) extracted fromGinkgo biloba. It is synthesized from geranylgeranyl pyrophosphate (GGPP).

应用

(-)-Bilobalide fromGinkgo bilobaleaves has been used as a reference substance to study the antimicrobial activity of different fractions ofG.bilobaleaves against a number of Gram-positive and negative bacteria and yeasts.

包装

25, 100 mg in poly bottle
10 mg in glass insert

生化/生理作用

Bilobalide is an inducer of cytochrome P450 enzymes CYP3A1 and CYP1A2. It exhibits neuroprotective, anti-inflammatory, anti-oxidative and anti-apoptotic properties. Bilobalide, a γ-aminobutyric acid (GABA) A_A-rho, 5-hydroxytryptamine type 3 (5-HT(3)) receptor antagonist, may be used to study the function of these receptors in the brain processes such as cognition and memory. It serves as a specific platelet-activating factor receptor antagonist, which helps in the treatment of cardiovascular (Alzheimer′s disease) and cerebrovascular diseases.
Bioactive terpenoid found inGinkgo biloba.

基本信息

经验(实验)分子式	C15H18O8
分子量	326.30
MDL编号	MFCD00238547
PubChem化学物质编号	24892116

半岛bd体育手机客户端 性质

生物来源	plant leaves (Ginkgo biloba)
质量水平	100
测定	≥93% (HPLC)
形式	powder
technique(s)	HPLC: suitable
颜色	white
储存温度	?20℃
SMILES string	CC(C)(C)[C@]1(O)CC2OC(=O)C[C@@]23C(=O)OC4OC(=O)[C@H](O)[C@]134
InChI	1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6-,8-,11-,13-,14+,15+/m0/s1
InChI key	MOLPUWBMSBJXER-YDGSQGCISA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)