半岛bd体育手机客户端 说明
一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
生化/生理作用
FK-506是一种有效的免疫抑制剂,神经保护和神经再生剂,以及体外T细胞增殖阻滞剂。FK-506可破坏T淋巴细胞中钙调神经磷酸酶介导的信号转导,并与FK-506结合蛋白-12(FKBP12)相互作用。
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
USP issued SDS can be found here.
Sales restrictions may apply.
基本信息
经验(实验)分子式 | C44H69NO12· H2O |
分子量 | 822.03 |
MDL编号 | MFCD11045918 |
PubChem化学物质编号 | 329751216 |
NACRES | NA.24 |
半岛bd体育手机客户端 性质
等级 | pharmaceutical primary standard |
manufacturer/tradename | USP |
application(s) | pharmaceutical (small molecule) |
格式 | neat |
SMILES string | O.CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]2OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@]4(O)O[C@H]([C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)OC)[C@H](C[C@H]4C)OC |
InChI | 1S/C44H69NO12.H2O/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52,57-40)41(49)42(50)45-17-12-11-14-32(45)43(51)56-39(29(6)34(47)24-35(31)48)27(4)21-30-15-16-33(46)36(23-30)53-7;/h10,19,21,26,28-34,36-40,46-47,52H,1,11-18,20,22-24H2,2-9H3;1H2/b25-19+,27-21+;/t26-,28+,29+,30-,31+,32-,33+,34-,36+,37-,38-,39+,40+,44+;/m0./s1 |
InChI key | NWJQLQGQZSIBAF-MLAUYUEBSA-N |
Gene Information | human ... FKBP1A(2280) |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H301 |
预防措施声明 | P301 + P330 + P331 + P310 |
危险分类 | Acute Tox. 3 Oral |
储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich