半岛bd体育手机客户端 说明
一般描述
Cyclohexylaminoethanesulfonic acid (CHES) is a buffering agent. Its structure contains a hydrophilic taurine (2-aminoethanesulfonic acid) moiety and a hydrophobic cyclohexyl group. CHES binds to the active site of several enzymes and inhibits substrate binding and enzymatic activity. Therefore, CHES may be used as a scaffold for new drug development for regulating enzyme activity.
应用
2-(Cyclohexylamino)ethanesulfonic acid (CHES) has been used in the preparation of dimethyl trisulfide- polysorbate 80 (DMTS-PS80) formulation.
其他说明
Buffer for studying pH-dependent processes in enzymology; Has a high affinity for the iodoacetate binding site of liver alcohol dehydrogenase.
基本信息
经验(实验)分子式 | C8H17NO3S |
分子量 | 207.29 |
Beilstein | 2967601 |
EC 号 | 203-115-6 |
MDL编号 | MFCD00003835 |
PubChem化学物质编号 | 57648360 |
NACRES | NA.25 |
半岛bd体育手机客户端 性质
半岛bd体育手机客户端 线 | BioUltra |
质量水平 | 200 |
测定 | ≥99.5% (T) |
形式 | powder |
杂质 | insoluble matter, passes filter test |
灼烧残渣 | ≤0.05% |
缺失 | ≤0.5% loss on drying, 110 ℃ |
pH值(酸碱度) | 3.0-5.0 (25 ℃, 0.5 M in H2O) |
有效pH范围 | 8.6 - 10.0 |
pKa (25 ℃) | 9.3 |
溶解性 | H2O: 0.5 M at 20 ℃, clear, colorless |
痕量阴离子 | chloride (Cl-): ≤50 mg/kg sulfate (SO42-): ≤500 mg/kg |
痕量阳离子 | Al: ≤5 mg/kg As: ≤0.1 mg/kg Ba: ≤5 mg/kg Bi: ≤5 mg/kg Ca: ≤10 mg/kg Cd: ≤5 mg/kg Co: ≤5 mg/kg Cr: ≤5 mg/kg Cu: ≤5 mg/kg Fe: ≤5 mg/kg K: ≤50 mg/kg Li: ≤5 mg/kg Mg: ≤5 mg/kg Mn: ≤5 mg/kg Mo: ≤5 mg/kg Na: ≤50 mg/kg Ni: ≤5 mg/kg Pb: ≤5 mg/kg Sr: ≤5 mg/kg Zn: ≤5 mg/kg |
λ | 0.5 M in H2O |
紫外吸收 | λ: 260 nm Amax: 0.08 λ: 280 nm Amax: 0.05 |
SMILES string | OS(=O)(=O)CCNC1CCCCC1 |
InChI | 1S/C8H17NO3S/c10-13(11,12)7-6-9-8-4-2-1-3-5-8/h8-9H,1-7H2,(H,10,11,12) |
InChI key | MKWKNSIESPFAQN-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich