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位置:首页 > 品牌 > Sigma-Aldrich > Anti-CD3e (Mouse), PE-Cy7, clone 145-2C11 Antibody

Anti-CD3e (Mouse), PE-Cy7, clone 145-2C11 Antibody

品牌
Sigma-Aldrich
货号
MABF158A
规格纯度
clone 145-2C11, from hamster(Armenian), PE-Cy7
价格
1415.25 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-CD3e (Mouse), PE-Cy7, clone 145-2C11 Antibody
T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3e
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The 145-2C11 antibody is specific for mouse CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells. The 145-2C11 antibody is a widely used phenotypic marker for mouse T cells. In addition, binding of 145-2C11 antibody to CD3e can induce cell activation.

免疫原

Immunogen information for this antibody is proprietary information.

应用

Research Sub Category
Immunoglobulins & Immunology
This armenian hamster monoclonal Anti-CD3e Antibody (Mouse), PE-Cy7, clone 145-2C11, Cat. No. MABF1582 is validated for use in Flow Cytometry, for the detection of CD3e.
Research Category
Inflammation & Immunology

质量

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 1 μg from a representative lot detected CD3e in one million C57Bl/6 splenocytes.

外形

Purified Armenian Hamster monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Purified by size-exclusion chromatography

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.44

半岛bd体育手机客户端 性质

生物来源hamster (Armenian)
质量水平100
偶联物PE-Cy7
抗体形式purified antibody
antibody product typeprimary antibodies
克隆145-2C11, monoclonal
species reactivitymouse
包装antibody small pack of 25 μg
technique(s)flow cytometry: suitable
同位素/亚型IgG
UniProt登记号P22646

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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