Human Chondrocytes-Rheumatoid Arthritis: HC-RA, adult

半岛bd体育手机客户端 说明

一般描述

HC-RA Human Chondrocytes are derived from human articular cartilage of donors with rheumatoid arthritis (RA). Rheumatoid arthritis is an inflammatory disease that is characterized by overproliferation of synovial cells and their infiltration into adjacent joint tissues, accompanied by gradual destruction of cartilage and bone erosion. Normally, chondrocytes are responsible for producing and maintaining the extracellular matrix of cartilage, but in RA cartilage, the environment is changed significantly due to inflammation and the invasion of other cells. Therefore, HC-RA can be a useful model to study the effects of those changes on chondrocyte biology. In parallel with normal HC, HC-RA can be used to investigate the differences between normal and pathological joints and evaluate potential treatment strategies.

Characterization: Positive for aggrecan after differentiation.

细胞系来源

Cartilage

应用

model to study effects of RA on chondrocytes, investigate differences between normal and pathological joints and evaluate potential treatment strategies

组分

Basal Medium containing 10% FBS & 10% DMSO

制备说明

• 1st passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 10 doublings

传代培养常规

Please refer to the HC-RA Culture Protocol.

基本信息

NACRES

NA.81

半岛bd体育手机客户端 性质

生物来源	human articular cartilage (rheumatoid arthritic)
质量水平	100
包装	pkg of 500,000 cells
生长模式	Adherent
核型	2n = 46
形态学	chondrocyte
technique(s)	cell culture | mammalian: suitable
相关疾病	arthritis
运输	dry ice
储存温度	?196℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable