半岛bd体育手机客户端 说明
一般描述
HScAEC, along with human aortic (HAOEC), carotid artery (HCtAEC), coronary artery (HCAEC) and brachiocephalic artery (HBcAEC) have been used to demonstrate that not only blood vessels from different tissues are highly heterogeneous, they also interact differently with leukocytes during the inflammation response (Scott, 2013). The authors further showed that differential N-glycosylation of commonly expressed vascular adhesion molecules may be responsible for this heterogeneity, as well as for modulation of signaling under resting and activated inflammatory conditions. This also explains why specific vascular beds may be more or less susceptible to particular diseases or stimuli. Importantly, if cells from different sources were used, these results could not be convincingly validated due to a number of uncontrolled variables, such as age, race, genetic variability or life style choices of the donors.
Because of the complex heterogeneity that exists not only between different donors, but even between different vascular beds in the same individual, it would be prudent to confirm any new findings on primary cell lots coming from several different origins.
细胞系来源
Artery
应用
blood pressure, blood supply, tissue oxygenation
组分
Basal Medium containing 10% FBS & 10% DMSO
制备说明
传代培养常规
Please refer to the HScAEC Culture Protocol.
基本信息
| NACRES | NA.81 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 生物来源 | human subclavian artery (normal) |
| 包装 | pkg of 500,000 cells |
| 生长模式 | Adherent |
| 核型 | 2n = 46 |
| 形态学 | Endothelial |
| technique(s) | cell culture | mammalian: suitable |
| 相关疾病 | bipolar disorder; cardiovascular diseases; cancer |
| 运输 | dry ice |
| 储存温度 | ?196℃ |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
