Human Lung Microvascular Endothelial Cells: HLMVEC, adult

半岛bd体育手机客户端 说明

一般描述

The pulmonary vasculature is of great physiological/pathological significance. It is now recognized to be a tissue composed of metabolically active, functionally responsive cells, that interact with circulating substrates and regulate the composition of systemic arterial blood, affect target organ functions, and contribute to thrombosis, hemostasis and immune reactions, as well as tumor metastasis. Human Lung Microvascular Endothelial Cells (HLMVEC) provide a useful tool for studying various aspects of pathology and biology of the pulmonary microvasculature in vitro.

HLMVEC have been used to elucidate the therapeutic effects of Angiotensin I-converting enzyme (ACE) inhibitors, and the results revealed that they provide an additional benefit to patients by activating bradykinin B1 receptor leading to prolonged nitric oxide (NO) production in endothelial cells and inhibition of PKCε (Ignjatovic, 2004; Stanisavljevic, 2006).

细胞系来源

Lungs

应用

lung physiology, metabolism, regulate blood composition, hemostasis, immune reactions, therapeutic effects, leukocyte migration,

组分

Cell Basal Medium containing 10% FBS & 10% DMSO

制备说明

• 3rd passage, >500,000 cells in Cell Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 15 doublings

传代培养常规

Please refer to the HLMVEC Culture Protocol.

基本信息

NACRES

NA.81

半岛bd体育手机客户端 性质

生物来源	human lung (normal)
质量水平	100
包装	pkg of 500,000 cells
生长模式	Adherent
核型	2n = 46
形态学	Endothelial
technique(s)	cell culture | mammalian: suitable
相关疾病	metastasis
运输	dry ice
储存温度	?196℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable