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位置: 首页> 品牌> Sigma-Aldrich> 5-氨基-2-羟基苯甲酸

5-Aminosalicylic Acid

5-氨基水杨酸

品牌
Sigma-Aldrich
CAS
89-57-6
货号
A3537
规格纯度
≥99%
价格
4106.83 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
89-57-6
5-Aminosalicylic Acid
5-Amino-2-hydroxybenzoic Acid
Mesalamine
5-AS
5-氨基水杨酸
氨水杨酸
5-氨基-2-羟基苯甲酸
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

5-Aminosalicylic acid (5-ASA) has been used:

  • to synthesize 5-formyl-aminosalicylate-inulin to quantify its release duringin vitrodigestion and fermentation and compare thein vitrofermentation properties of the conjugated inulin to native inulin
  • in cell adhesion assay to study its effects on E-cadherin glycosylation and membranous turnover
  • to evaluate its effects on the neutrophilic inflammation index (NII) phenotype to study the effectiveness of the high cholesterol diet-gut inflammation (HCD-GI) platform


5-氨基水杨酸是一种适用于 ELISA 分析的过氧化物酶底物。该底物生成棕色的可溶性终产物,该产物可通过分光光度法在 450nm 处读取。加入 3N NaOH 可终止反应,然后在 550nm 处进行读取。

包装

25, 100 g in poly bottle

生化/生理作用

5-Aminosalicylic acid (5-ASA) is a first-line medicine, used to treat inflammatory bowel diseases like ulcerative colitis (UC). It has a high-efficiency rate in maintenance and induction of remission. 5-ASA is an active component of sulfasalazine and also consists of the carbohydrate polymer, inulin. It might exhibit anti-oxidant activity to lessen tissue injury. 5-ASA is vital for the prevention of T cell activation and proliferation. It negatively regulates cyclooxygenase and lipoxygenase pathways and lowers the formation of prostaglandins and leukotrienes. 5-ASA stimulates the membranous expression of E-cadherin and boosts intercellular adhesion.

基本信息

线性分子式 H2NC6H3-2-(OH)CO2H
分子量 153.14
Beilstein 2090421
EC 号 201-919-1
MDL编号 MFCD00007877
PubChem化学物质编号 24890780
NACRES NA.83

半岛bd体育手机客户端 性质

质量水平 200
测定 ≥99%
形式 powder
颜色 off-white to gray
mp 275-280 ℃ (dec.) (lit.)
溶解性 1 M HCl: 50 mg/mL, clear, yellow to brown
储存温度 2-8℃
SMILES string Nc1ccc(O)c(c1)C(O)=O
InChI 1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)
InChI key KBOPZPXVLCULAV-UHFFFAOYSA-N
Gene Information human ... ALOX5(240), PPARG(5468), PTGS1(5742), PTGS2(5743)

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 2
闪点(F) 536.0 °F
闪点(C) 280 ℃
个人防护装备 dust mask type N95 (US), Eyeshields, Gloves

Sigma-Aldrich

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