半岛bd体育手机客户端 说明
应用
5-Aminosalicylic acid (5-ASA) has been used:
包装
25, 100 g in poly bottle
生化/生理作用
5-Aminosalicylic acid (5-ASA) is a first-line medicine, used to treat inflammatory bowel diseases like ulcerative colitis (UC). It has a high-efficiency rate in maintenance and induction of remission. 5-ASA is an active component of sulfasalazine and also consists of the carbohydrate polymer, inulin. It might exhibit anti-oxidant activity to lessen tissue injury. 5-ASA is vital for the prevention of T cell activation and proliferation. It negatively regulates cyclooxygenase and lipoxygenase pathways and lowers the formation of prostaglandins and leukotrienes. 5-ASA stimulates the membranous expression of E-cadherin and boosts intercellular adhesion.
基本信息
线性分子式 | H2NC6H3-2-(OH)CO2H |
分子量 | 153.14 |
Beilstein | 2090421 |
EC 号 | 201-919-1 |
MDL编号 | MFCD00007877 |
PubChem化学物质编号 | 24890780 |
NACRES | NA.83 |
半岛bd体育手机客户端 性质
质量水平 | 200 |
测定 | ≥99% |
形式 | powder |
颜色 | off-white to gray |
mp | 275-280 ℃ (dec.) (lit.) |
溶解性 | 1 M HCl: 50 mg/mL, clear, yellow to brown |
储存温度 | 2-8℃ |
SMILES string | Nc1ccc(O)c(c1)C(O)=O |
InChI | 1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11) |
InChI key | KBOPZPXVLCULAV-UHFFFAOYSA-N |
Gene Information | human ... ALOX5(240), PPARG(5468), PTGS1(5742), PTGS2(5743) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 2 |
闪点(F) | 536.0 °F |
闪点(C) | 280 ℃ |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich