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位置: 首页> 品牌> Sigma-Aldrich> Anti-HDAC11 Antibody

Anti-HDAC11 Antibody

品牌
Sigma-Aldrich
货号
09-827
规格纯度
from rabbit, purified by affinity chromatography
价格
6694.05 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-HDAC11 Antibody
histone deacetylase 11
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation is a marker for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.

特异性

This antibody recognizes HDAC11.

免疫原

Epitope: Amino Acid: 228-246
Linear Peptide corresponding to human HDAC11 at amino acids 228-246.

应用

Western Blot (SNAP ID) Analysis: 0.5 ?g/ml from a representative lot detected HDAC11 on 10 ?g of human brain tissue lysate.


Anti-HDAC11 Antibody is a Rabbit Polyclonal Antibody for detection of HDAC11 also known as histone deacetylase 11 & has been validated in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histone Modifying Proteins

Cell Cycle, DNA Replication & Repair

质量

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 0.05 ?g/ml of this antibody detected HDAC11 on 10 ?g of human brain tissue lysate.

目标描述

39 kDa

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Human brain tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity human, mouse, rat
technique(s) western blot: suitable
NCBI登记号 NP_079103.2
UniProt登记号 Q96DB2
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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