半岛bd体育手机客户端 说明

一般描述

Dimethyl chloromalonate (dimethyl 2-chloromalonate) is a dialkyl 2-substituted malonate. Carbanions of dimethyl chloromalonate are reported to react with naphthoquinone derivatives, via vicarious nucleophilic substitution or oxidative nucleophilic substitution of hydrogen processes. Dimethyl chloromalonate is reported to react with hydroquinone and monosubstituted hydroquinones to afford 2-oxido-benzo[b]furan derivatives. Synthesis of dimethyl 2-chloromalonate, via chlorination of dimethyl malonate has been reported.

应用

Dimethyl chloromalonate is suitable for use in the synthesis of 4,5,6-trichloropyrimidine. It may be used in the stereoselective synthesis of highly functionalized nitrocyclopropanes. It may be used in one-pot synthesis of tetra-alkoxycarbonylallylidenetriphenylphosphoranes.

包装

25, 100 g in glass bottle

基本信息

线性分子式	ClCH(COOCH3)2
分子量	166.56
Beilstein	1768415
EC 号	249-275-0
MDL编号	MFCD00042837
PubChem化学物质编号	24863315
NACRES	NA.22

半岛bd体育手机客户端 性质

质量水平	200
测定	94%
杂质	4-5% dimethyl dichloromalonate
折射率	n 20/D 1.437 (lit.)
bp	105-106 ℃/19 mmHg (lit.)
密度	1.305 g/mL at 25 ℃ (lit.)
SMILES string	COC(=O)C(Cl)C(=O)OC
InChI	1S/C5H7ClO4/c1-9-4(7)3(6)5(8)10-2/h3H,1-2H3
InChI key	LNBQBURECUEBKZ-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H314
预防措施声明	P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
危险分类	Skin Corr. 1B
储存分类代码	8A - Combustible, corrosive hazardous materials
WGK	WGK 3
闪点(F)	224.6 °F - closed cup
闪点(C)	107 ℃ - closed cup
个人防护装备	Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter