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位置: 首页> 品牌> Sigma-Aldrich> CD71 (MRQ-48) Mouse Monoclonal Antibody

CD71 (MRQ-48) Mouse Monoclonal Antibody

品牌
Sigma-Aldrich
货号
171M-9
包装型号
规格纯度
价格
2166.15 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
CD71 (MRQ-48) Mouse Monoclonal Antibody
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The transferrin receptor (CD71) is most highly expressed on placental syncytiotrophoblasts, myocytes, basal keratinocytes, hepatocytes, endocrine pancreas, spermatocytes, and erythroid precursors. The level of transferrin receptor expression is highest in early erythroid precursors through the intermediate normoblast phase, after which expression decreases through the reticulocyte phase. The maturation of erythrocytes results in loss of transferrin receptor expression, in concert with down-regulation of the machinery for hemoglobin synthesis. The high level of transferrin receptor within erythroid precursors makes it an excellent marker for evaluation of erythroid components within bone marrow. Anti-CD71 is a highly effective marker for highlighting erythroid precursors in bone marrow biopsy specimens and shows the following features: 1) distinct membranous and cytoplasmic staining pattern, which is easily recognized in bone marrow biopsy; 2) restriction to erythroid lineage within bone marrow biopsy specimens; 3) CD71 expression decreases with the maturation of erythrocytes, with the highest level seen in early forms and the lowest level in late normoblast stage, and most importantly; 4) mature erythrocytes do not express CD71, which facilitates bone marrow analyses.Anti-CD71 is useful in identifying erythroid precursors with very little interference from mature erythrocytes and also in the determination of erythroid leukemia, benign erythroid proliferative disorders, and myelodysplastic syndrome, although further studies are needed for making a definitive diagnosis of MDS.

质量


IVD

IVD

IVD

RUO

联系

CD71 Positive Control Slides, Product No. 171S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 500
100
生物来源 mouse
偶联物 unconjugated
抗体形式 culture supernatant
antibody product type primary antibodies
克隆 MRQ-48, monoclonal
描述 For In Vitro Diagnostic Use in Select Regions (See Chart)
形式 buffered aqueous solution
species reactivity human
包装 vial of 0.1 mL concentrate (171M-94)
vial of 0.5 mL concentrate (171M-95)
bottle of 1.0 mL predilute (171M-97)
vial of 1.0 mL concentrate (171M-96)
bottle of 7.0 mL predilute (171M-98)
manufacturer/tradename Cell Marque?
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
同位素/亚型 IgG1
控制 bone marrow
运输 wet ice
储存温度 2-8℃
可视化 cytoplasmic, membranous

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