CD57 (NK-1) Mouse Monoclonal Antibody

半岛bd体育手机客户端 说明

一般描述

CD57 is a marker expressed in the membrane of NK cells and other T cells. It is often used in the identification of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) to visualize the small T-cells that ring the LP cells (rosettes of follicular T cells around the large neoplastic LP cells). These features can be used to distinguish NLPHL from T-cell/histiocyte-rich large B-cell lymphoma, which usually shows no rosettes of CD57-positive follicular T-cells around the large tumor cells. Anti-CD57 also reacts with neuroendocrine cells and their derived tumors, including neuroendocrine tumors of diverse origins, pheochromocytomas, paragangliomas, medulloblastoma, and varying proportions of neural tumors such as schwannomas, neurofibromas, neuromas, and granular cell tumors. However, anti-CD57 lacks the specificity of chromogranin and synaptophysin for detecting neuroendocrine neoplasms and therefore should be considered in a panel. Anti-CD57 can also be useful in separating thymoma from thymic carcinoma when combined with a panel that includes antibodies against CD5 and CD117.

质量

IVD

IVD

IVD

RUO

联系

CD57 Positive Control Slides, Product No. 157S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

质量水平	500 100
生物来源	mouse
偶联物	unconjugated
抗体形式	diluted ascites fluid
antibody product type	primary antibodies
克隆	NK-1, monoclonal
描述	For In Vitro Diagnostic Use in Select Regions (See Chart)
形式	buffered aqueous solution
species reactivity	human
包装	vial of 0.1 mL concentrate (157M-94) vial of 0.5 mL concentrate (157M-95) bottle of 1.0 mL predilute (157M-97) vial of 1.0 mL concentrate (157M-96) bottle of 7.0 mL predilute (157M-98)
manufacturer/tradename	Cell Marque?
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
同位素/亚型	IgMκ
控制	tonsil
运输	wet ice
储存温度	2-8℃
可视化	membranous