半岛bd体育手机客户端 说明
一般描述
Human germinal center–associated lymphoma (HGAL) protein is specifically expressed in the cytoplasm of germinal center B-cells, but is absent in mantle and marginal zone B-cells and in the interfollicular and paracortical regions in normal tonsils and lymph nodes. Its high degree of specificity for germinal center B-cells makes anti-HGAL an ideal marker for the detection of germinal center-derived B-cell lymphomas. Anti-HGAL has the highest overall sensitivity of detecting follicular lymphoma (FL) and in detecting the interfollicular and diffuse components of FL compared with antibodies against bcl2, LMO2, CD10, and bcl6. The addition of anti-HGAL to the immunohistologic panel is beneficial in the work-up of nodal and extranodal B-cell lymphomas, and the efficacy of anti-HGAL in detecting the follicular, interfollicular, and diffuse components of FL is of particular value in the setting of variant immunoarchitectural patterns.
质量
IVD |
IVD |
IVD |
RUO |
联系
HGAL Positive Control Slides, Product No. 375S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.
Download the latest released IFU
Note: This IFU may not apply to your specific product lot.
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
半岛bd体育手机客户端 性质
质量水平 | 500 100 |
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | culture supernatant |
antibody product type | primary antibodies |
克隆 | MRQ-49, monoclonal |
描述 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
形式 | buffered aqueous solution |
species reactivity | human |
包装 | vial of 0.1 mL concentrate (375M-94) vial of 0.5 mL concentrate (375M-95) bottle of 1.0 mL predilute (375M-97) vial of 1.0 mL concentrate (375M-96) bottle of 7.0 mL predilute (375M-98) |
manufacturer/tradename | Cell Marque? |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
同位素/亚型 | IgG2aκ |
控制 | lymph node, tonsil |
运输 | wet ice |
储存温度 | 2-8℃ |
可视化 | cytoplasmic |
Sigma-Aldrich