HBTU

半岛bd体育手机客户端 说明

一般描述

TBTU and HBTU are two of the most popular in situ activation reagents used in solid phase and solution phase peptide synthesis [1-9]. These reagents offer reactivity similar to symmetrical anhydrides and BOP [1]. Couplings proceed smoothly and rates can even be enhanced by the addition of HOBt [2, 4, 5, 6]. In addition to having high reactivity, TBTU and HBTU have also been shown to limit enantiomerization during fragment condensation and during DMAP catalyzed esterification of arginine derivatives [3]. Comparative experiments between HBTU and TBTU have shown that the counter ion has no influence on coupling rates or levels of enantiomerization [1].

The product number for this product was previously 01-62-0010.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

联系

Replaces: 01-62-0010

分析说明

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1?mmole in 2 ml DMF): clearly soluble

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C11H16F6N5OP
分子量	379.24
MDL编号	MFCD00075445
EC索引号	423-020-5

半岛bd体育手机客户端 性质

质量水平	300
半岛bd体育手机客户端 线	Novabiochem?
测定	≥99.0% (HPLC)
形式	powder
效能	>2000 mg/kg LD50, oral (Rat)
reaction suitability	reaction type: Coupling Reactions
manufacturer/tradename	Novabiochem?
pH值(酸碱度)	4.1 (1.6 g/L in H2O)
mp	250 ℃
溶解性	1.6 g/L
application(s)	peptide synthesis
储存温度	2-8℃
InChI	1S/C11H16N5O/c1-14(2)11(15(3)4)17-16-10-8-6-5-7-9(10)12-13-16/h5-8H,1-4H3/q+1
InChI key	CLZISMQKJZCZDN-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H315 - H317 - H319 - H334 - H335
预防措施声明	P261 - P264 - P280 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable