Anti-IGF2 mRNA-binding protein 3 Antibody

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一般描述

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5′ UTR of the insulin-like growth factor 2 leader 3 mRNA and may repress translation of insulin-like growth factor 2 during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq].

特异性

This antibody recognizes IGF2 mRNA-binding protein 3 at the C-terminus.

免疫原

KLH-conjugated linear peptide corresponding to human IGF2 mRNA-binding protein 3 at and around the C-terminus.
Epitope: C-terminus

应用

This Anti-IGF2 mRNA-binding protein 3 Antibody is validated for use in WB for the detection of IGF2 mRNA-binding protein 3.
Research Sub Category
Growth Factors & Receptors
Research Category
Apoptosis & Cancer
Western Blot (SNAP ID) Analysis: 2 ?g/mL from a previous lot detected IGF2 mRNA-binding protein 3 on 10 ?g of Hek293 cell lysate.

Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP.

质量

Evaluated by Western Blot in Hek293 cell lysate.

Western Blot Analysis: 0.5 ?g/mL of this antibody detected IGF2 mRNA-binding protein 3 on 10 ?g of Hek293 cell lysate.

目标描述

64 kDa was observed. Predicted to cross-react with all the Isoforms of IGF2BP3.

外形

Affinity purified
Purified rabbit serum in PBS with 0.09% azide.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Hek293 cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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