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位置: 首页> 品牌> Sigma-Aldrich> Anti-Calcineurin Aα Antibody

Anti-Calcineurin Aα Antibody

品牌
Sigma-Aldrich
货号
07-1492
规格纯度
from rabbit, purified by affinity chromatography
价格
5734.65 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-Calcineurin Aα Antibody
NFAT transcription complex cytosolic component, nuclear factor of activated T-cells, cytoplasmic,, calcineurin-dependent 1, nuclear factor of activated T-cells, cytosolic component 1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Calcineurin is a serine/threonine protein phosphatase involved in the mediation of signal transduction in a wide variety of cellular responses. Calcineurin has been linked to Pmk1 MAP kinase and PI pathways, as well as to members of the small GTPase Rab/Ypt family and Type II myosin. Furthermore, calcineurin participates in the transduction of extracellular signals to the nucleus by dephosphorylation of members of the NFAT family of transcription factors. These linkages demonstrate calcineurin′s multifunctional capabilities in the regulation of calcium signaling. The Aα form of calcineurin is a major catalytic subunit gene isoform of calcineurin in most tissues that allows differentiation of Aα from the Aβ and Aγ isoforms.

特异性

This antibody recognizes the Aα form of calcineurin.

免疫原

KLH-conjugagted synthetic peptide corresponding to Calcineurin Aα.

应用

Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
Research Category
Signaling
This Anti-Calcineurin Aα Antibody is validated for use in WB for the detection of Calcineurin Aα.

质量

Evaluated by Western Blot in Mouse brain lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected Calcineurin on 10 ?g of mouse brain lysate.

目标描述

58 kDa

联系

Replaces: AB1696

外形

Affinity purified
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH7.4) 150 mM NaCl with 40% gylerol. Contains no preservative.

储存及稳定性

Store at -20°C for up to 12 months in undiluted aliquots; at this temperature the solution will
remain unfrozen.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

分析说明

Control
Mouse brain lysate

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity rat, human, mouse
species reactivity (predicted by homology) mammals (based on 100% sequence homology)
technique(s) western blot: suitable
NCBI登记号 NP_000935.1
UniProt登记号 Q08209
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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