您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> Anti-phospho-VEGFR2/Flk-1/KDR (Tyr1054) Antibody

Anti-phospho-VEGFR2/Flk-1/KDR (Tyr1054) Antibody

品牌
Sigma-Aldrich
货号
07-722
规格纯度
Upstate?, from rabbit
价格
5016.79 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-phospho-VEGFR2/Flk-1/KDR (Tyr1054) Antibody
Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, kinase insert domain receptor (a type III receptor tyrosine kinase), vascular endothelial growth factor receptor 2
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The Flt gene family of receptor tyrosine kinases includes Flt-1, KDR/Flk-1, Flt-3, and Flt-4. They encode receptors for VEGF, characterized by seven Ig-loops within their extracellular domain and a split kinase domain within the cytoplasmic domain. VEGF is an important angiogenic factor of many solid tumors and is also involved in the differentiation of endothelial cells. Flt-1 (Fms-like tyrosine kinase, VEGF-R1) is expressed on endothelial cells and on the common precursors of endothelial and hematopoietic stem cells. KDR (Flk-1, VEGF-R2) is the principal receptor involved in VEGF signaling. KDR is expressed on endothelial cells and stimulates angiogenesis, but is also expressed on bone marrow cells, and is thought to play a role in driving the proliferation of most or all leukemic cells. Flt3 (also known as Flk-2) is a class III receptor tyrosine kinase that is closely related to c-Kit and c-Fms. It is expressed in primitive hematopoietic cells and its ligand exerts proliferative effects on these cells in co-operation with other cytokines.

特异性

Recognizes VEGFR2/Flk-1/KDR when phosphorylated on Tyrosine 1054 (human).

免疫原

Synthetic peptide encompassing

应用

Anti-phospho-VEGFR2/Flk-1/KDR (Tyr1054) Antibody is an antibody against phospho-VEGFR2/Flk-1/KDR (Tyr1054) for use in WB.
Research Category
Signaling

质量

Western Blot Analysis:
This lot detected VEGFR2 phosphorylated on Tyr1054 at a 1:1,000 dilution in PAE cells transfected with CSF/KDR and treated with 40ng/mL CSF-1 for 15 min. Cell lysate resolved via SDS-PAGE and transferred to PVDF (Immobilon-P).

目标描述

152 kDa

外形

Double affinity purified
Affinity purified rabbit polyclonal IgG in PBS with 0.05% NaN3 and 50% glycerol.

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
CSF-1 treated PAE cell lysate, transfected with CSF/KDR.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity purified immunoglobulin
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity human, zebrafish
species reactivity (predicted by homology) mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), horse (based on 100% sequence homology), chicken (based on 100% sequence homology),Danio(based on 100% sequence homology), rat (based on 100% sequence homology), primate (based on 100% sequence homology)
manufacturer/tradename Upstate?
technique(s) western blot: suitable
NCBI登记号 NM_002253.2
UniProt登记号 P35968
运输 dry ice
Gene Information human ... KDR(3791)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 2

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map