Anti-Nitrotyrosine Antibody

半岛bd体育手机客户端 说明

一般描述

Nitrotyrosine has been identified as an indicator of cell damage and inflammation, as well as of the production of NO. It is believed that measuring the concentration of nitrotyrosine will serve as a marker for damage caused by NO in the cell. Previous studies have shown that nitrotyrosine has been found in inflammatory conditions such as atherosclerotic plaques and rheumatoid arthritis, among others.

特异性

Recognizes proteins which are nitrated.

免疫原

Nitrated KLH

应用

Research Sub Category
Neurotransmitters & Receptors

Neurodegenerative Diseases
This Anti-Nitrotyrosine Antibody is published in more than 80 citations and validated for use in Immunocytochemistry (IC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB) for the detection of Nitrotyrosine.
Research Category
Neuroscience

质量

routinely evaluated by immunoblot on nitrotyrosine immunoblotting controls (Catalog #12-354)

目标描述

Predicted MW for nitrated-BSA: 85 kDa

外形

ImmunoAffinity Purified
Purified Rabbit IgG in buffer containing 0.1M Tris-Glycine, 0.15M NaCl, pH 7.4, 0.05% sodium azide, and 10 mg/mL BSA
Format: Purified

储存及稳定性

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

分析说明

Control
Immunohistochemistry: Human Alzheimer disease brain sections; mouse liver
Immunoblotting: Nitrated-BSA
Indirect ELISA: Nitrated-BSA
Indirect immunofluorescence: A549 cells metabolically labeled with 3-nitrotyrosine

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity purified immunoglobulin
antibody product type	primary antibodies
克隆	polyclonal
species reactivity (predicted by homology)	all
manufacturer/tradename	Upstate?
technique(s)	immunocytochemistry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable
同位素/亚型	IgG
运输	dry ice

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable