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位置: 首页> 品牌> Sigma-Aldrich> Anti-Ipaf (NLRC4) Antibody

Anti-Ipaf (NLRC4) Antibody

品牌
Sigma-Aldrich
货号
06-1125
规格纯度
from rabbit, purified by affinity chromatography
价格
4848.93 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-Ipaf (NLRC4) Antibody
NLR family, CARD domain containing 4, NOD-like receptor C4, caspase recruitment domain family, member 12, ICE-protease activating factor, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4, NLR family CARD domain-
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Ipaf, also known as NLRC4, is a human CED-4 homologue and is thought to be an activator of pro-caspase-1 and might also be associated with the activation of caspase-1 as a response to pro-inflammatory and apoptotic stimulus. It has been shown to be induced by p53 and contributes to p53-dependent apoptosis. Ipaf is thought to play a role in the activation of the innate immune system.

特异性

This antibody recognizes Ipaf at the LRR4 domain.

免疫原

Epitope: LRR4 domain
KLH-conjugated linear peptide corresponding to human Ipaf (NLRC4) at the LRR4 domain.

应用

Research Sub Category
Apoptosis - Additional
Western Blot Analysis: 1 ug/ml of this antibody detected Ipaf in 10 ug of human lung tissue lysate.

Immunocytochemistry Analysis: A 1:500 dilution from a previous lot detected Ipaf in NIH/3T3 cells.
Research Category
Apoptosis & Cancer
This Anti-Ipaf (NLRC4) Antibody is validated for use in IC, WB for the detection of Ipaf (NLRC4).

质量

Evaluated by Western Blot in human lung tissue lysate.

Western Blot Analysis: 1 ?g/mL of this antibody detected Ipaf in 10 ?g of human lung tissue lysate.

目标描述

~112 kDa observed.

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Human lung tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity mouse, human
technique(s) immunocytochemistry: suitable
western blot: suitable
NCBI登记号 NP_067032
UniProt登记号 Q9NPP4
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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