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位置: 首页> 品牌> Sigma-Aldrich> Anti-Axin-1 Antibody

Anti-Axin-1 Antibody

品牌
Sigma-Aldrich
货号
06-1049
规格纯度
from rabbit, purified by affinity chromatography
价格
4848.93 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Axin-1 Antibody
Axin-1, Axis inhibition protein 1, hAxin
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Axin-1 is a beta-catenin destruction complex scaffold protein and a transcription factor of the Wnt signaling pathway. Variation in the Wnt signaling pathway has been associated with the formation of some primary human cancers. Axin-1 mutation has been linked to oral squamous cell carcinoma. Axin-1 binds to GSK3alpha and activates the Wnt signaling pathway which is shown to be associated with growth and development of cells. Axin-1 has also been implicated in Alzheimer′s disease.

免疫原

KLH-conjugated linear peptide corresponding to human Axin-1.

应用

Anti-Axin-1 Antibody is an antibody against Axin-1 for use in WB, IC, IH.
Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected Axin-1 in A431 and HeLa cells.

Immunohistochemistry Analysis: 1:1,000 dilution from a representative lot detected Axin-1 in human kidney and human skin tissues.

质量

Evaluated by Western Blot in HEK293 cell lysate.

Western Blot Analysis: 1 ?g/mL of this antibody detected Axin-1 on 10 ?g of HEK293 cell lysate.

目标描述

~110 kDa observed. An uncharacterized band appears at ~40 and 45 kDa in some lysates.

外形

Affinity purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity human, mouse
technique(s) immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
NCBI登记号 NP_003493
UniProt登记号 O15169
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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