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位置: 首页> 品牌> Sigma-Aldrich> Rabbit anti-ErbB2 Antibody, Affinity Purified

Rabbit anti-ErbB2 Antibody, Affinity Purified

品牌
Sigma-Aldrich
货号
PLA0123
规格纯度
Powered by Bethyl Laboratories, Inc.
价格
6227.32 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Rabbit anti-ErbB2 Antibody, Affinity Purified
CD antigen CD340
HER2
neuro/glioblastoma derived oncogene homolog
CD340
HER-2/neu
c-erb B2/neu protein
TKR1
p185erbB2
NGL
metastatic lymph node gene 19 protein
proto-oncogene Neu
HER-2
neuroblastoma/glioblastoma derived oncogene homolog
tyrosine kinase-type cell surface receptor HER2
human epidermal growth factor receptor 2
proto-oncogene c-ErbB-2
NEU
MLN 19
herstatin
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

The epitope recognized by PLA0123 maps to a region between residue 1200 and the C-terminus (residue 1255) of human v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 using the numbering given in entry NP_004439.2 (GeneID 2064).

外形

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

其他说明

ErbB2 is a member of the receptor tyrosine kinase family of proteins. The four members of this family are ErbB1 (Epidermal growth factor receptor; EGFR/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). The ErbB receptor members are single-pass transmembrane proteins with an extracellular ligand-binding domain and a cytoplasmic tyrosine-kinase domain. The epidermal growth factor (EGF) and its related proteins serve as the ligands for the ErbB receptors. Upon binding, the receptors heterodimerize, autophosphorylate and make contact with adapter molecules to transmit cellular signals involved in cell proliferation, survival, and differentiation. The ErbB2 receptor is the only member that does not interact with a ligand, but instead functions as a heterodimeric partner to coordinate signals from other ligand bound ErbB receptors. Amplification and/or overexpression of ErbB2 have been reported in many cancers.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity purified immunoglobulin
antibody product type primary antibodies
等级 Powered by Bethyl Laboratories, Inc.
species reactivity human
technique(s) immunohistochemistry: 1:100- 1:500
immunoprecipitation (IP): 1-4 μg/mg
western blot: 1:2,000- 1:10,000
登记号 NP_004439.2
UniProt登记号 P04626
运输 wet ice
储存温度 2-8℃
Gene Information rabbit ... ErbB2(2064)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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