Anti-IRAK-M antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

The IRAKM (interleukin-1 receptor-associated kinase-3) gene is mapped to human chromosome 12q14.3. This gene is predominantly expressed in monocytes and macrophages.

免疫原

IRAK-M antibody was raised against a peptide corresponding to amino acids from the carboxy terminus of human IRAK-M .

应用

Anti-IRAK-M antibody produced in rabbit has been used in Western blotting, immunoprecipitation and immunofluorescence.

生化/生理作用

The Irakm (interleukin-1 receptor-associated kinase-3) protein downregulates the toll like receptor (TLR)-signalling and influences the action of nuclear factor-κB (NF-κB). Increased IRAKM expression is observed in inflammatory bowel disease (IBD) and colorectal cancer. It is known to reduce the immune response against microorganism.

特点和优势

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联系

The action of this antibody can be blocked using blocking peptide SBP3500193.

外形

Supplied in PBS with 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD03096977
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	predicted mol wt 66 kDa
species reactivity	human, rat, mouse
technique(s)	immunofluorescence: suitable immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable
NCBI登记号	AF113136
UniProt登记号	Q9Y616
运输	dry ice
储存温度	?20℃
Gene Information	human ... IRAK3(11213)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable