半岛bd体育手机客户端 说明
一般描述
Tumor suppressor candidate 3 (TUSC3) codes for a subunit of the endoplasmic reticulum-bound oligosaccharyltransferase complex. It is a 348 amino acid protein, that has 11 exons spanning ～224 Kbp of the genomic DNA. TUSC3 has five potential transmembrane domains and is located on human chromosome 8p22.
免疫原
The antiserum was produced against synthesized peptide derived from human TUSC3.
Immunogen Range:131-180
应用
Anti-TUSC3 antibody has been used in immunohistochemistry, immunoblotting and co-immunoprecipitation.
生化/生理作用
Tumor suppressor candidate 3 (TUSC3) is a tumor suppressor gene, that is responsible for autosomal recessive mental retardation. It participates in catalyzing the transfer of a 14-sugar oligosaccharide from dolichol to nascent protein. Absence of TUSC3 is associated with lymph node metastasis in larynx and pharynx squamous cell carcinomas.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
半岛bd体育手机客户端 性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 39 kDa |
| species reactivity | mouse, human, rat |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:10000 immunofluorescence: 1:100-1:500 western blot: 1:500-1:1000 |
| NCBI登记号 | Q13454 |
| UniProt登记号 | Q13454 |
| 运输 | wet ice |
| 储存温度 | ?20℃ |
| Gene Information | human ... TUSC3(7991) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
